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Table 2 Immunohistochemical and molecular profile of uterine PEComas

From: TFE3-associated perivascular epithelioid cell tumor with complete response to mTOR inhibitor therapy: report of first case and literature review

Case no HMB 45 MELAN A CATHEPSIN K TFE 3 SMA DESMIN Caldesmon Ki 67 FISH
1 Positive 0 Positive Positive 0 0 ns - Not done
2 3+ 3+ - 3+ 0 - - 2+ +
3 4+ 2+ 4+ 4+ 0 0 0 ns +
4 4+ 0 4+ 4+ 0 0 0 ns +
5 4+ 1+ 4+ 4+ 0 1+ 0 ns +
6 4+ 0 4+ 4+ - 0 0 ns +
7 3+ + - 3+ + + - 5% Not done
8 4+ - 4+ 4+ 4+ - - ns PSF-TFE3
9 Positive Ns Positive Positive Focal positive - - Ns Not done
10 Positive Positive Positive Positive - - - 5% +
Present case 4+ 4+ - 3+ - - 1+ 30% Not done
  1. Note: ns not specified