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Table 2 The KEGG pathway analysis of activated memory CD4 T cells and CD8 T cell-related genes in the Comparative Toxicogenomics Database. The KEGG pathway analysis of activated memory CD4 T cell-related genes

From: Screening and analysis of RNAs associated with activated memory CD4 and CD8 T cells in liver cancer

ID Description p value p.adjust q value Count gene_symbol
hsa04514 Cell adhesion molecules (CAMs) 1.98E-10 1.98E-10 8.55E-09 11 CTLA4/CD8A/CD8B/TIGIT/HLA-DRB1/ICOS/CD86/HLA-DPB1/HLA-DQA1/HLA-DRA/HLA-DPA1
hsa04658 Th1 and Th2 cell differentiation 9.90E-10 9.90E-10 2.14E-08 9 IL12RB1/TBX21/HLA-DRB1/CD3D/HLA-DPB1/HLA-DQA1/HLA-DRA/HLA-DPA1/LCK
hsa04640 Hematopoietic cell lineage 1.92E-09 1.92E-09 2.76E-08 9 CD8A/CD8B/HLA-DRB1/CD3D/HLA-DPB1/HLA-DQA1/HLA-DRA/FCGR1A/HLA-DPA1
hsa04659 Th17 cell differentiation 3.86E-09 3.86E-09 4.16E-08 9 IL12RB1/TBX21/HLA-DRB1/CD3D/HLA-DPB1/HLA-DQA1/HLA-DRA/HLA-DPA1/LCK
hsa04060 Cytokine-cytokine receptor interaction 2.07E-05 2.07E-05 3.58E-05 9 CXCL9/CCL4/CCL5/IL12RB1/CD27/CXCR6/CXCL13/CXCR3/CCR5
hsa04612 Antigen processing and presentation 6.37E-09 6.37E-09 4.58E-08 8 CD8A/CD8B/CD74/HLA-DRB1/HLA-DPB1/HLA-DQA1/HLA-DRA/HLA-DPA1
hsa05323 Rheumatoid arthritis 2.61E-08 2.61E-08 1.41E-07 8 CTLA4/CCL5/HLA-DRB1/CD86/HLA-DPB1/HLA-DQA1/HLA-DRA/HLA-DPA1
hsa05322 Systemic lupus erythematosus 4.29E-07 4.29E-07 1.23E-06 8 HLA-DRB1/CD86/HLA-DPB1/FCGR3A/HLA-DQA1/HLA-DRA/FCGR1A/HLA-DPA1
hsa04145 Phagosome 1.19E-06 1.19E-06 2.70E-06 8 HLA-DRB1/HLA-DPB1/FCGR3A/HLA-DQA1/OLR1/HLA-DRA/FCGR1A/HLA-DPA1
hsa05152 Tuberculosis 4.24E-06 4.24E-06 8.72E-06 8 CD74/HLA-DRB1/HLA-DPB1/FCGR3A/HLA-DQA1/HLA-DRA/FCGR1A/HLA-DPA1
hsa04062 Chemokine signaling pathway 6.10E-06 6.10E-06 1.14E-05 8 CXCL9/CCL4/CCL5/CXCR6/CXCL13/CXCR3/CCR5/GNGT2
hsa04672 Intestinal immune network for IgA production 5.76E-09 5.76E-09 4.58E-08 7 HLA-DRB1/ICOS/CD86/HLA-DPB1/HLA-DQA1/HLA-DRA/HLA-DPA1
hsa05320 Autoimmune thyroid disease 1.02E-08 1.02E-08 6.27E-08 7 CTLA4/HLA-DRB1/CD86/HLA-DPB1/HLA-DQA1/HLA-DRA/HLA-DPA1
hsa05321 Inflammatory bowel disease (IBD) 4.38E-08 4.38E-08 1.72E-07 7 IL12RB1/TBX21/HLA-DRB1/HLA-DPB1/HLA-DQA1/HLA-DRA/HLA-DPA1
hsa05140 Leishmaniasis 1.44E-07 1.44E-07 4.45E-07 7 HLA-DRB1/HLA-DPB1/FCGR3A/HLA-DQA1/HLA-DRA/FCGR1A/HLA-DPA1
hsa04660 T cell receptor signaling pathway 1.14E-06 1.14E-06 2.70E-06 7 CTLA4/CD8A/CD8B/ICOS/CD3D/LCP2/LCK
hsa04380 Osteoclast differentiation 4.63E-06 4.63E-06 9.08E-06 7 SIRPG/LILRB2/LILRB1/FCGR3A/FCGR1A/LCP2/LCK
hsa05166 Human T cell leukemia virus 1 infection 0.000148 0.000148 0.000237 7 HLA-DRB1/CD3D/HLA-DPB1/HLA-DQA1/HLA-DRA/HLA-DPA1/LCK
hsa05168 Herpes simplex virus 1 infection 0.014966 0.014966 0.018997 7 CCL5/CD74/HLA-DRB1/HLA-DPB1/HLA-DQA1/HLA-DRA/HLA-DPA1
hsa05330 Allograft rejection 4.14E-08 4.14E-08 1.72E-07 6 HLA-DRB1/CD86/HLA-DPB1/HLA-DQA1/HLA-DRA/HLA-DPA1
hsa05332 Graft-versus-host disease 6.67E-08 6.67E-08 2.40E-07 6 HLA-DRB1/CD86/HLA-DPB1/HLA-DQA1/HLA-DRA/HLA-DPA1
hsa04940 Type I diabetes mellitus 8.97E-08 8.97E-08 2.98E-07 6 HLA-DRB1/CD86/HLA-DPB1/HLA-DQA1/HLA-DRA/HLA-DPA1
hsa05416 Viral myocarditis 6.88E-07 6.88E-07 1.75E-06 6 HLA-DRB1/CD86/HLA-DPB1/HLA-DQA1/HLA-DRA/HLA-DPA1
hsa05145 Toxoplasmosis 2.67E-05 2.67E-05 4.44E-05 6 HLA-DRB1/HLA-DPB1/HLA-DQA1/HLA-DRA/CCR5/HLA-DPA1
hsa05164 Influenza A 0.000272 0.000272 0.000419 6 CCL5/HLA-DRB1/HLA-DPB1/HLA-DQA1/HLA-DRA/HLA-DPA1
hsa05169 Epstein-Barr virus infection 0.000665 0.000665 0.000989 6 HLA-DRB1/CD3D/HLA-DPB1/HLA-DQA1/HLA-DRA/HLA-DPA1
hsa05310 Asthma 5.48E-07 5.48E-07 1.48E-06 5 HLA-DRB1/HLA-DPB1/HLA-DQA1/HLA-DRA/HLA-DPA1
hsa04620 Toll-like receptor signaling pathway 0.002276 0.002276 0.003274 4 CXCL9/CCL4/CCL5/CD86
hsa04650 Natural killer cell mediated cytotoxicity 0.005222 0.005222 0.007042 4 FCGR3A/SH2D1A/LCP2/LCK
hsa04623 Cytosolic DNA-sensing pathway 0.004625 0.004625 0.006439 3 CCL4/CCL5/ZBP1
hsa04662 B cell receptor signaling pathway 0.00961 0.00961 0.012568 3 LILRB2/CD72/LILRB1