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Table 2 Values are hazard ration (HR) [95% confidential intervals]. Stage IV patients were excluded from analysis of disease-free survival

From: Skeletal muscle wasting and long-term prognosis in patients undergoing rectal cancer surgery without neoadjuvant therapy

  Overall survival Disease-free survival Tumor-specific survival
Age 1.06 (1.03–1.09, p < 0.001) 1.03 (0.99–1.07, p = 0.137) 1.02 (0.99–1.06, p = 0.211)
Sex, female 0.79 (0.43–1.44, p = 0.444) 0.67 (0.27–1.64, p = 0.376) 0.69 (0.32–1.52, p = 0.360)
BMI 0.88 (0.80–0.96, p = 0.006) 0.88 (0.77–1.00, p = 0.046) 0.88 (0.78–0.98, p = 0.025)
CCI 1.36 (1.20–1.53, p < 0.001) 1.23 (1.01–1.50, p = 0.039) 1.31 (1.12–1.53, p = 0.001)
ASA score
 2 vs 1 0.45 (0.10–1.97, p = 0.291) 0.95 (0.13–7.14, p = 0.957) 0.73 (0.09–5.57, p = 0.758)
 3 vs 1 1.21 (0.29–5.07, p = 0.796) 1.43 (0.19–10.93, p = 0.731) 1.22 (0.16–9.22, p = 0.850)
SMI, yes 3.15 (1.76–5.65, p < 0.001) 2.25 (0.93–5.45, p = 0.073) 2.99 (1.43–6.23, p = 0.004)
VO, yes 1.02 (0.54–1.94, p = 0.947) 1.97 (0.84–4.61, p = 0.118) 0.85 (0.36–1.98, p = 0.703)
IMFAR, yes 1.28 (0.69–2.40, p = 0.435) 0.71 (0.26–1.92, p = 0.495) 0.78 (0.32–1.92, p = 0.590)
SO, yes 0.72 (0.36–1.46, p = 0.367) 1.36 (0.55–3.33, p = 0.506) 0.31 (0.09–1.02, p = 0.054)
SATI, yes 0.78 (0.38–1.61, p = 0.503) 1.31 (0.51–3.35, p = 0.575) 0.52 (0.18–1.51, p = 0.231)
VATI, yes 0.36 (0.15–0.86, p = 0.021) 0.74 (0.27–2.01, p = 0.560) 0.18 (0.04–0.77, p = 0.021)
Laparoscopy, yes 0.49 (0.07–3.62, p = 0.485) 0.11 (0.01–0.89, p = 0.039) 0.36 (0.05–2.67, p = 0.315)
Severe complication, yes 0.84 (0.32–2.18, p = 0.717) 0.16 (0.02–1.24, p = 0.079) 0.85 (0.26–2.77, p = 0.792)
Tumor location
 Middle vs high 1.28 (0.67–2.46, p = 0.454) 0.67 (0.23–1.93, p = 0.461) 1.18 (0.50–2.75, p = 0.710)
 Low vs high 1.37 (0.63–2.98, p = 0.434) 1.64 (0.57–4.72, p = 0.362) 1.46 (0.56–3.85, p = 0.441)
TNM stage
 II vs I 1.63 (0.68–3.94, p = 0.277) 1.23 (0.33–4.58, p = 0.759) 3.00 (0.61–14.87, p = 0.179)
 III vs I 1.68 (0.72–3.93, p = 0.232) 2.88 (0.94–8.84, p = 0.064) 5.53 (1.25–24.51, p = 0.024)
 IV vs I 4.32 (1.65–11.27, p = 0.003) 14.96 (3.16–70.84, p = 0.001)
Radicality
 R1 vs R0 4.97 (2.27–10.87, p < 0.001) 7.96 (3.27–19.39, p < 0.001)
Adjuvant chemotherapy, yes 1.19 (0.66–2.17, p = 0.563) 2.36 (0.92–6.04, p = 0.072) 2.62 (1.11–6.19, p = 0.028)
  1. BMI Body mass index, CCI Charlson comorbidity index, ASA American Society of Anesthesiologists, SMI Skeletal muscle index, VATI Visceral adipose tissue index, SATI Subcutaneous adipose tissue index, VO Visceral obesity, SO Sarcopenic obesity