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Table 1 Correlations between SII and clinicopathological factors of GC patients before and after PSM

From: Correlation analysis between preoperative systemic immune inflammation index and prognosis of patients after radical gastric cancer surgery: based on propensity score matching method

Parameters

Before PSM

After PSM

H-SII (n = 240)

L-SII (n = 531)

χ2

P

H-SII (n = 177)

L-SII (n = 177)

χ2

P

Age (years)

  

3.415

0.065

  

0.011

0.915

 ≤ 60

129(53.75%)

323(60.83%)

  

100(56.50%)

99(55.93%)

  

 > 60

111(46.25%)

208(39.17%)

  

77(43.50%)

78(44.07%)

  

Gender

  

0.097

0.756

  

0.000

1.000

 Male

187(77.92%)

419(78.91%)

  

138(77.97%)

138(77.97%)

  

 Female

53(22.08%)

112(21.09%)

  

39(22.03%)

39(22.03%)

  

Smoking

  

0.234

0.628

  

0.011

0.915

 Yes

113(47.08%)

260(48.96%)

  

84(47.46%)

83(46.89%)

  

 No

127(52.92%)

271(51.04%)

  

93(52.54%)

94(53.11%)

  

Drinking

  

1.246

0.264

  

1.457

0.227

 Yes

91(37.92%)

224(42.18%)

  

72(40.68%)

61(34.46%)

  

 No

149(62.08%)

307(57.82%)

  

105(59.32%)

116(65.54%)

  

Tumor size (mm)

  

11.357

< 0.001

  

0.232

0.630

 ≤ 50

168(70.00%)

429(80.79%)

  

128(72.32%)

132(74.58%)

  

 > 50

72(30.00%)

102(19.21%)

  

49(27.68%)

45(25.42%)

  

Differentiation

  

4.188

0.041

  

0.000

1.000

 Well and moderately

73(30.42%)

202(38.04%)

  

61(34.46%)

61(34.46%)

  

 Poorly

167(69.58%)

329(61.96%)

  

116(65.54%)

116(65.54%)

  

Alb (g/L)

  

33.695

< 0.001

  

0.000

1.000

 ≤ 39.85

183(76.25%)

288(54.24%)

  

121(68.36%)

121(68.36%)

  

 > 39.85

57(23.75%)

243(45.76%)

  

56(31.64%)

56(31.64%)

  

WBC(W, × 109 cells/L)

  

107.173

< 0.001

  

0.113

0.737

 ≤ 6.525

119(49.58%)

451(84.93%)

  

118(66.67%)

115(64.97%)

  

 > 6.525

121(50.41%)

80(15.07%)

  

59(33.33%)

62(35.03%)

  

CEA

  

0.542

0.462

  

0.554

0.457

 ≤ 2.17 ug/ml

128(53.33%)

268(50.47%)

  

89(50.28%)

82(46.33%)

  

 > 2.17 ug/ml

112(46.67%)

263(49.53%)

  

88(49.72%)

95(53.67%)

  

CA199

  

0.835

0.361

  

0.0137

0.711

 ≤ 21 u/mL

179(74.58%)

412(77.59%)

  

135(76.27%)

132(74.58%)

  

 > 21 u/mL

61(25.42%)

119(22.41%)

  

42(23.73%)

45(25.42%)

  

CA125

  

6.671

0.010

  

1.532

0.216

 ≤ 14.6 u/ml

145(60.42%)

371(69.87%)

  

112(63.28%)

123(69.49%)

  

 > 14.6 u/ml

95(39.58%)

160(30.13%)

  

65(36.72%)

54(30.51%)

  

Type of surgery

  

5.572

0.062

  

4.974

0.084

 DG

80(33.33%)

217(40.87%)

  

57(32.21%)

39(22.04%)

  

 PG

78(32.50%)

172(32.39%)

  

59(33.33%)

63(35.59%)

  

 TG

82(34.17%)

142(26.74%)

  

61(34.46%)

75(42.37%)

  

TNM stage

  

11.509

0.003

  

2.425

0.298

 I

38(15.83%)

137(25.80%)

  

34(16.95%)

35(19.77%)

  

 II

43(17.92%)

105(19.78%)

  

31(17.51%)

40(22.60%)

  

 III

159(66.25%)

289(54.42%)

  

116(65.54%)

102(57.63%)

  
  1. H-SII high systemic immune inflammatory group, L-SII low systemic immune inflammatory group, ALb albumin, WBC white blood cell, DG distal gastectomy, PG proximal gastrectomy, TG total gastrectomy