Table 4 Effect of pre-perfusion and post-perfusion mSIS on surgical complications and local toxicity
Clavien-Dindo classification | p value | Wierberdink classification | p value | |||||||
Grade 1 | Grade 2 | Grade 3 | Grade 4 | Grade 5 | Grade 1 | Grade 2 | Grade 3 | |||
Pre-perfusion | ||||||||||
mSIS 0 | 6 | 1 | 0 | 1 | 0 | 0,188χ2 | 2 | 5 | 1 | 0.786χ2 |
mSIS 1 | 4 | 0 | 0 | 1 | 1 | 0 | 5 | 1 | ||
mSIS 2 | 2 | 2 | 2 | 0 | 0 | 1 | 4 | 1 | ||
Post-perfusion | ||||||||||
mSIS 0 | 1 | 0 | 0 | 0 | 0 | 0,555χ2 | 1 | 0 | 0 | 0.110χ2 |
mSIS 1 | 4 | 0 | 0 | 0 | 1 | 1 | 4 | 0 | ||
mSIS 2 | 7 | 3 | 2 | 2 | 0 | 1 | 10 | 3 | ||
Clavien-Dindo classification | Wieberdink toxicity grading | |||||||||
Grade I | Any deviation from the normal post-operative course without need of intervention | No visible effect | ||||||||
Grade II | Complication requiring pharmacological treatment | Slight erythema and/or edema | ||||||||
Grade III | Complication requiring surgical,endoscopic, or radiological intervention | Considerable erythema and/or edema with blistering | ||||||||
Grade IV | Life threatening complication requiring admission to intensive care unit | Extensive epidermolysis and/or obvious damage to deep tissues with a threatened or actual compartment syndrome | ||||||||
Grade V | Death | Severe tissue damage necessitating amputation | ||||||||