Table 2 The association between clinicopathological characteristics and PD-L1

Age

0.898

0.698

 < 60

80

47 (24%)

33 (23%)

80

49 (25%)

31 (22%)

 ≥ 60

258

149 (76%)

109 (77%)

258

151 (75%)

107 (78%)

Gender

0.599

0.429

 Male

205

120 (61%)

85 (60%)

133

125 (62%)

80 (58%)

 Female

133

76 (39%)

57 (40%)

205

75 (38%)

58 (42%)

Tumor site

0.518

0.216

 Rectum

91

49 (25%)

42 (30%)

91

52 (26%)

39 (28%)

 Left colon

112

68 (35%)

44 (31%)

112

74 (37%)

38 (28%)

 Right colon

135

79 (40%)

56 (39%)

135

74 (37%)

61 (44%)

Tumor diameter

0.123

0.077

 < 5 cm

166

89 (45%)

77 (53%)

166

90 (45%)

76 (55%)

 ≥ 5 cm

172

107 (55%)

65 (47%)

172

110 (55%)

62 (45%)

Tumor differentiation

0.797

0.521

 Moderate

256

147 (75%)

109 (77%)

256

154 (76%)

102 (75%)

 Poor

82

49 (25%)

33 (23%)

82

46 (24%)

36 (25%)

Pathological T stage

< 0.001^*

0.177

 I–II

77

28 (14%)

49 (35%)

65

39 (20%)

26 (19%)

 III

261

168 (86%)

93 (65%)

231

161 (80%)

70 (81%)

Lymph node metastasis

0.034^*

0.370

 No

198

105 (54%)

93 (65%)

198

113 (57%)

85 (62%)

 Yes

140

91 (46%)

49 (35%)

140

87 (43%)

53 (38%)

Tumor budding

0.039^*

0.563

 Negative (< 5 buds)

123

62 (32%)

61 (43%)

123

67 (34%)

56 (41%)

 Positive (≥ 5 buds)

215

134 (68%)

81 (57%)

215

133 (66%)

82 (59%)

Vessel invasion

0.250

0.425

 No

218

121 (62%)

97 (68%)

272

126 (63%)

91 (66%)

 Yes

120

75 (38%)

45 (32%)

67

74 (37%)

47 (34%)

Intraneural invasion

0.849

0.614

 No

307

177 (90%)

130 (92%)

307

181 (91%)

126 (91%)

 Yes

31

19 (10%)

12 (8%)

31

19 (9%)

12 (9%)

Tumor deposit

0.018^*

0.866

 No

297

165 (84%)

132 (93%)

297

174 (87%)

123 (89%)

 Yes

41

31 (16%)

10 (7%)

41

26 (13%)

15 (11%)

Histological type

0.314

0.471

 Adenocarcinoma

297

169 (86%)

128 (90%)

297

175 (88%)

122 (88%)

 Mucinous/SRCC

41

27 (14%)

14 (10%)

41

25 (12%)

16 (12%)

Bowel perforation

< 0.001^*

0.859

 No

325

185 (94%)

140 (99%)

332

192 (96%)

133 (96%)

 Yes

13

11 (6%)

2 (9%)

13

8 (4%)

5 (4%)

Ulceration

0.825

0.738

 No

193

113 (58%)

80 (56%)

193

116 (58%)

77 (56%)

 Yes

145

83 (42%)

62 (44%)

145

84 (42%)

61 (44%)

TNM stage

0.037^*

0.020^*

 I

185

97 (49%)

88 (61%)

184

104 (52%)

80 (58%)

 II

 III

155

99 (51%)

56 (39%)

138

96 (48%)

42 (42%)

 IV

Schistosomiasis

0.650

0.210

 Negative

210

124 (63%)

86 (61%)

210

130 (65%)

80 (58%)

 Positive

128

72 (37%)

56 (39%)

128

70 (35%)

58 (42%)

CD8⁺ T cell density

0.001^*

0.023^*

 Low group

1044

74 (38%)

30 (21%)

104

71 (36%)

33 (24%)

 High group

234

122 (62%)

112 (79%)

234

129 (64%)

105 (76%)