Table 2 Univariate and multivariate analysis of risk factors in relation to OS in ICC

 Female

112

1.145 (0.982‑1.336)

0.075

 Male

125

 < 60

108

0.942 (0.694‑1.279)

0.695

 ≥ 60

129

 Low

207

2.620 (1.739‑3.948)

< 0.001

2.201 (1.438‑3.371)

< 0.001

 High

30

 Low

201

1.886 (1.267‑2.806)

0.001

1.610 (1.061‑2.442)

0.025

 High

36

 Low

93

1.222 (0.889‑1.680)

0.204

 High

144

 < 5

142

1.392 (1.024‑1.893)

0.030

1.115 (0.806‑1.544)

0.510

 ≥ 5

95

 Single

167

1.379 (1.017‑1.890)

0.046

1.307 (0.941‑1.815)

0.110

 Multiple

70

 No

134

1.728 (1.273‑2.345)

< 0.001

1.321 (0.774‑2.255)

0.308

 Yes

103

 No

133

1.673 (1.233‑2.271)

0.001

1.187 (0.782‑1.801)

0.421

 Yes

104

 No

206

1.279 (0.829‑1.972)

0.252

 Yes

31

 W+M

144

0.915 (0.671‑1.247)

0.563

 P

93

 I+II

127

1.649 (1.214‑2.238)

0.001

1.162 (0.739‑1.825)

0.516

 III+IV

110

 < 25

165

0.866 (0.623‑1.205)

0.381

 ≥ 25

72

 < 5

134

1.172 (0.863‑1.590)

0.297

 ≥ 5

103

 < 37

141

1.201 (0.883‑1.635)

0.231

 ≥ 37

96

 < 17.1

92

0.908 (0.665‑1.240)

0.534

 ≥ 17.1

145

 < 35

163

1.137 (0.823‑1.573)

0.424

 ≥ 35

74

 < 40

96

1.098 (0.803‑1.502)

0.547

 ≥ 40

141

 No

139

0.895 (0.657‑1.220)

0.472

 Yes

98