Fig. 3

The association between plasma PROK1 and PROK1 expression in primary cancer lesion. A A representative picture of the specimen stained with hematoxylin-eosin (magnification, × 200). B A representative picture of PROK1-positive primary cancer lesion (magnification, × 200). The PROK1 was positive in the cytoplasm of cancer cells. In this case, most of the cancer cells were positive for PROK1. C The plasma PROK1-positive patients were identified more commonly in the immunohistochemistry (IHC) positive group than the IHC negative group