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Table 1 Characteristic of included studies: FoxP3+Treg cells and survival outcome

From: The prognostic value of intratumoral and peritumoral tumor-infiltrating FoxP3+Treg cells in of pancreatic adenocarcinoma: a meta-analysis

study

M/F

Tumor stage

Marker

Location

Number(H/L)

Cutoff

Outcome

Wartenberg M 201 5[22]

120(64/53)

3/98/4/10 (I/II/III/IV)

FoxP3+

I

53/55

Median normalized value

OS

    

P

50/58

Median normalized value

OS

Tang Y 201 4[23]

45(28/17)

34/11 (I+II/III+IV)

CD4+CD25+Foxp3+

I

22/23

Median value

OS

Wang X 201 5[24]

120(66/54)

28/92 (I+II/III+IV)

FoxP3+

I

76/44

Not mentioned

OS

       

PFS

Ino Y 201 3[4]

212(132/80)

2/188/0/22 (I/II/III/IV)

FoxP3+ CD4+

 

106/64

Not mentioned

OS

       

PFS

Liu L 201 6[25]

92(68/24)

25/41/26 (I/II/III)

FoxP3+

I

44/48

Median value

OS

       

PFS

    

P

36/56

Median value

OS

       

PFS

Hiraoka N 200 6[26]

198(114/84)

16/10/74/98 (I/II/III/IV)

FoxP3+

I

104/94

Not mentioned

OS

Diana A 201 6[27]

145(77/68)

88/57 (I+II/III+IV)

FoxP3+

I

38/107

Not mentioned

OS

    

I

  

DFS

Zhang K 201 5[28]

40(26/14)

4/16/0/6 (I/II/III/IV)

FoxP3+

I

24/16

Not mentioned

OS

  1. I Intratumoral; P Peritumoral; H high level; L low level