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Table 1 Framework for perioperative care of patients with rectal cancer (2001‑2008)

From: Efficacy of endoscopic surveillance in the detection of local recurrence after radical rectal cancer surgery is limited? A retrospective study

Type of treatment

Resectability status

pTNM classification (MRI or CT)

Tumor localization

Preoperative sRTa

Resectable

cT3 and/or N+

Middle or low rectum

Preoperative RTb or preoperative CRTc

Unresectable or probably not R0

cT3-4 and/or N+

 

No RT

Resectable, contraindications

cT1-2, N0

 

cT3 and/or N+

High rectum

Postoperative RTd or postoperative CRTe

Not preoperative RT

pT3-4 and/or N+

 

Postoperative CTxf

 

T4 and/or N+

 
  1. Abbreviations: CRT Chemoradiotherapy, CT Computed tomography, CTx Chemotherapy, MRI Magnetic resonance imaging, pTNM Pathological TNM classification, RT Radiotherapy, sRT Short-course radiotherapy
  2. aShort-course radiotherapy (5 × 5 Gy) followed by immediate surgery (< 10 days from the first radiation fraction)
  3. b45‑50 Gy in 28 fractions; a boost with a further 5.4 Gy
  4. c45‑50 Gy in 28 fractions; a boost with a further 5.4 Gy combined with 2 cycles of 5-fluorouracil
  5. d45‑54 Gy per fraction
  6. e1.8‑2.0 Gy per fraction combined with 4‑6 cycles of 5-fluorouracil
  7. f6 cycles of 5-fluorouracil