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Table 1 Main characteristics of studies included in meta-analysis

From: Prognostic and clinicopathological importance of microRNA-140 expression in cancer patients: a meta-analysis

Author Year Study region Recruitment time Sample size Cancer type Detection method Detected sample Cutoff scores (high/low) Analysis method OS, HR estimation Quality score
Hao Y 2013 China 2004-2007 120 HCC qRT-PCR Tissues Median Univariate/multivariate analysis 0.47 (0.25-0.9) 8
Fang Z 2017 China NS 144 GC ISH Tissue Optimal cutoff Univariate/multivariate analysis 0.505 (0.319-0.801) 7
Li J 2017 China NS 63 CRC qRT-PCR Blood Median Univariate analysis 0.77 (0.65-0.92) 6
Cha Y 2018 China 2011-2015 60 GC qRT-PCR Tissue Median Univariate analysis 0.39 (0.17-0.93) 7
Zhou Y 2019 China 2010-2012 73 BC qRT-PCR Tissue Median Univariate analysis 0.79 (0.65-0.96) 7
Zhang H 2020 China 2014-2016 200 NPC qRT-PCR Blood Median Univariate analysis 1.04 (0.41-2.62) 6
Zou X 2020 China 2014-2016 208 NPC qRT-PCR Blood Median Univariate analysis 0.85 (0.37-1.98) 6
He Y 2020 China NS 104 CM qRT-PCR Tissue Optimal cutoff Univariate/multivariate analysis 0.8 (0.39-0.92) 7
Yang H 2020 China 1998-2003 113 ESCC qRT-PCR Tissues Optimal cutoff Multivariate analysis 0.84 (0.67-1.05) 8
Yu Q 2020 China 2009-2013 122 TC qRT-PCR Tissues Optimal cutoff Multivariate analysis 0.369 (0.152-0.898) 8
Wu Q 2020 China 2013-2018 105 NPC qRT-PCR Tissues Optimal cutoff Univariate analysis 0.57 (0.41-0.8) 7
Huang C 2020 China NS 74 RCC qRT-PCR Tissues Optimal cutoff Multivariate analysis 1.16 (1.01-1.33) 7
  1. HCC hepatocellular carcinoma, GC gastric cancer, CRC colorectal cancer, BC breast cancer, NPC nasopharyngeal carcinoma, CM cutaneous melanoma, ESCC esophageal squamous cell carcinoma, TC thyroid cancer, RCC renal cell carcinoma, qRT-PCR quantitative real-time PCR, ISH in situ hybridization, NS data were not shown, OS overall survival, HR hazard ratio