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Table 3 Univariate analysis and multivariate analysis

From: Does the primary tumour location affect the prognosis of patients with colorectal cancer peritoneal metastases treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy?

Variables

Overall survival

Univariate analysis

Multivariate analysis

HR (95% CI)

P

HR (95% CI)

P

Sex: male/female

1.32 (0.66–2.64)

0.434

  

Age at operation

1.02 (0.98–1.05)

0.283

  

Preoperative chemotherapy (no/yes)

1.22 (0.53–2.80)

0.635

  

Synchronous/metachronous

1.46 (0.73–2.93)

0.288

  

Site of original (rectum/colon)

2.54 (1.24–5.18)

0.011

2.15 (1.15–4.93)

0.035

Histology (mucinous/adenocarcinoma)

1.53 (0.78–3.00)

0.215

  

Preoperative CEA level

1.00 (0.99–1.00)

0.279

  

Preoperative CA19-9 level

1.00 (0.99–1.00)

0.247

  

HIPEC regimen (lobaplatin/non-lobaplatin)

0.63 (0.31–1.28)

0.199

1.39 (0.65–2.94)

0.394

Presence of ascites (yes/no)

1.33 (0.68–2.60)

0.410

  

PCI score

1.09 (1.03–1.14)

0.002

1.05 (0.98–1.12)

0.140

CC score (2–3/0–1)

3.49 (1.77–6.87)

< 0.001

1.99 (1.06–4.17)

0.047

Grade 3–4 postoperative complication (no/yes)

1.63 (0.77–3.42)

0.201

  

Leukopenia (no/yes)

0.67 (0.28–1.63)

0.382

  

Neutropenia (no/yes)

0.80 (0.33–1.94)

0.626

  

Thrombocytopenia (no/yes)

0.49 (0.15–1.63)

0.245

  

BRAF status (mutation/no mutation)

1.58 (0.79–3.13)

0.266

  

MSI (MSS/MSI-H)

1.27 (0.61–2.73)

0.573

  

Adjuvant therapy (yes/no)

0.76 (0.35–1.65)

0.489

  

Colostomy or ileostomy (yes/no)

1.39 (0.71–2.74)

0.334

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