Fig. 8

Circ-RNF111 silencing repressed tumor growth in vivo. A Tumor volume was monitored. B Xenograft tumors were presented. C Tumor weight was examined after 32 days. D The levels of circ-RNF111, miR-876-3p, and KLF12 mRNA in collected tumors were detected by qRT-PCR assay. E The protein level of KLF12 in collected tumors was measured with western blot assay. F The levels of KLF12 and ki67 in collected tumors were evaluated by IHC assay. *P < 0.05, **P < 0.01