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Fig. 6 | World Journal of Surgical Oncology

Fig. 6

From: Circ-RNF111 aggravates the malignancy of gastric cancer through miR-876-3p-dependent regulation of KLF12

Fig. 6

MiR-876-3p overexpression repressed GC cell progression by interacting with KLF12. AGS and SNU-638 cells were administrated with miR-NC, miR-876-3p, miR-876-3p + pcDNA, or miR-876-3p + KLF12. A, B The mRNA and protein levels of KLF12 in AGS and SNU-638 cells were detected by qRT-PCR assay and western blot assay, respectively. C Cell viability, D colony formation, E apoptosis, F migration, G invasion, and H cell cycle process in AGS and SNU-638 cells were evaluated. I, J The protein levels of CyclinD1 and MMP9 in AGS and SNU-638 cells were measured via western blot assay. K–M The levels of glucose consumption, lactate production and ATP production in AGS and SNU-638 cells were examined with kits. N The protein level of HK-2 in AGS and SNU-638 cells was measured via western blot assay. **P < 0.01, ***P < 0.001

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