Fig. 3

Circ-RNF111 sponged miR-876-3p to regulate miR-876-3p expression. A MiR-876-3p contained the binding sites of circ-RNF111. B, C The interaction between circ-RNF111 and miR-876-3p was verified by dual-luciferase reporter assay and RIP assay. D, E The expression of miR-876-3p in GC tissues, cells, and normal tissues and cells was determined by qRT-PCR assay. F The linear correlation between the levels of circ-RNF111 and miR-876-3p in GC tissues was estimated. G, H After AGS and SNU-638 cells were administrated with si-NC, si-circ-RNF111, Vector, or circ-RNF111, the levels of circ-RNF111 and miR-876-3p were detected by qRT-PCR assay. ***P < 0.001