Fig. 7

Circ_0029803 knockdown inhibited the growth of CRC tumors by regulating miR-216b-5p/SKIL axis in vivo. After SW480 cells transfected with sh-circ_0029803 or control sh-NC were inoculated into the nude mice. A, B The tumors’ volume and weight in sh-circ_0029803 group and sh-NC group were measured. C–E The levels of circ_0029803, miR-216b-5p, and SKIL detected in tumor tissues were examined by qRT-PCR. F The protein level of SKIL was also detected in tumor tissues by western blot. G The abundance of SKIL in tumor tissues was identified by IHC staining analysis. *P<0.05