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Table 4 Cox regression analyses of prognostic variables for OS in surgery patients

From: Effect of surgery on survival in patients with stage III N2 small cell lung cancer: propensity score matching analysis and nomogram development and validation

Variable

Univariate analysis

Multivariate analysis

HR (95%CI)

p

HR (95%CI)

p

Age

1.020 (1.000–1.040)

0.036

1.018 (1.000–1.037)

0.046

Race

0.831 (0.496–1.390)

0.484

  

Sex

1.040 (0.758–1.420)

0.824

  

Year

0.947 (0.690–1.300)

0.739

  

Lateral

1.050 (0.946–1.160)

0.365

  

Procedure

 

0.907

  

 Sublobectomy

1

   

 Lobectomy

0.953 (0.689–1.318)

0.772

  

 Pneumonectomy

1.119 (0.483–2.592)

0.794

  

Number of examined lymph nodes

 

0.348

  

 ≤ 6

1

   

 ≥ 7

1.031 (0.715–1.486)

0.872

  

 Unknown

1.335 (0.876–2.034)

0.179

  

Number of positive lymph nodes ≥ 3 or unknown vs ≤ 2

1.510 (1.100–2.070)

0.010

1.447 (1.048–1.998)

0.025

T stage

 

0.022

  

 T1

1

 

1

 

 T2

1.406 (0.979–2.021)

0.065

1.325 (0.919–1.910)

0.132

 T3/T4

1.718 (1.154–2.557)

0.008

1.708 (1.135–2.571)

0.010

Radiation

0.640 (0.466–0.879)

0.006

0.684 (0.478–0.981)

0.039

Chemotherapy

0.684 (0.462–1.010)

0.059

0.784 (0.505–1.217)

0.278

  1. OS overall survival, CI confidence interval, HR hazards ratio