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Table 2 Cox regression analyses of prognostic variables for OS after PSM

From: Effect of surgery on survival in patients with stage III N2 small cell lung cancer: propensity score matching analysis and nomogram development and validation

Variable Univariate analysis Multivariate analysis
HR (95%CI) p HR (95%CI) p
Age   0.007   
 < 60 years 1   1  
 60–69 years 1.312 (0.984–1.750) 0.064 1.217 (0.911–1.626) 0.185
 ≥ 70 years 1.588 (1.186–2.126) 0.002 1.606 (1.197–2.156) 0.002
Race (other vs White) 0.976 (0.670–1.420) 0.898   
Sex (female vs male) 0.934 (0.752–1.160) 0.537   
Year (2010–2015 vs 2004–2009) 0.952 (0.764–1.190) 0.665   
Lateral (left vs right) 1.068(0.994– 1.148) 0.072 1.072 (0.997–1.152) 0.061
Grade   0.800   
 I–III 1    
 IV 0.936 (0.708–1.238) 0.645   
 Unknown 1.027 (0.801–1.317) 0.831   
Site   0.100   
 RUL 1    
 RML 1.436 (0.748–2.757) 0.277   
 RLL 0.808 (0.578–1.130) 0.212   
 LUL 1.107 (0.845–1.449) 0.461   
 LLL 1.266 (0.904–1.775) 0.170   
Tumor size   0.020   
 ≤ 3 cm 1    
 3–5 cm 1.173 (0.916–1.502) 0.206   
 > 5 cm 1.661 (1.168–2.362) 0.005   
T stage   0.020   
 T1 1   1  
 T2 1.050 (0.817–1.350) 0.703 1.023 (0.796–1.316) 0.859
 T3/T4 1.464 (1.112–1.925) 0.007 1.568 (1.189–2.068) 0.001
Surgery 0.716 (0.577–0.889) 0.003 0.572 (0.453–0.723) < 0.001
Radiation 0.625 (0.493–0.793) < 0.001 0.519 (0.401–0.670) < 0.001
Chemotherapy 0.743 (0.525–1.050) 0.093 0.796 (0.538–1.178) 0.253
  1. PSM propensity score matching, OS overall survival, CI confidence interval, HR hazards ratio