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Table 2 Cox regression analyses of prognostic variables for OS after PSM

From: Effect of surgery on survival in patients with stage III N2 small cell lung cancer: propensity score matching analysis and nomogram development and validation

Variable

Univariate analysis

Multivariate analysis

HR (95%CI)

p

HR (95%CI)

p

Age

 

0.007

  

 < 60 years

1

 

1

 

 60–69 years

1.312 (0.984–1.750)

0.064

1.217 (0.911–1.626)

0.185

 ≥ 70 years

1.588 (1.186–2.126)

0.002

1.606 (1.197–2.156)

0.002

Race (other vs White)

0.976 (0.670–1.420)

0.898

  

Sex (female vs male)

0.934 (0.752–1.160)

0.537

  

Year (2010–2015 vs 2004–2009)

0.952 (0.764–1.190)

0.665

  

Lateral (left vs right)

1.068(0.994– 1.148)

0.072

1.072 (0.997–1.152)

0.061

Grade

 

0.800

  

 I–III

1

   

 IV

0.936 (0.708–1.238)

0.645

  

 Unknown

1.027 (0.801–1.317)

0.831

  

Site

 

0.100

  

 RUL

1

   

 RML

1.436 (0.748–2.757)

0.277

  

 RLL

0.808 (0.578–1.130)

0.212

  

 LUL

1.107 (0.845–1.449)

0.461

  

 LLL

1.266 (0.904–1.775)

0.170

  

Tumor size

 

0.020

  

 ≤ 3 cm

1

   

 3–5 cm

1.173 (0.916–1.502)

0.206

  

 > 5 cm

1.661 (1.168–2.362)

0.005

  

T stage

 

0.020

  

 T1

1

 

1

 

 T2

1.050 (0.817–1.350)

0.703

1.023 (0.796–1.316)

0.859

 T3/T4

1.464 (1.112–1.925)

0.007

1.568 (1.189–2.068)

0.001

Surgery

0.716 (0.577–0.889)

0.003

0.572 (0.453–0.723)

< 0.001

Radiation

0.625 (0.493–0.793)

< 0.001

0.519 (0.401–0.670)

< 0.001

Chemotherapy

0.743 (0.525–1.050)

0.093

0.796 (0.538–1.178)

0.253

  1. PSM propensity score matching, OS overall survival, CI confidence interval, HR hazards ratio