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Table 3 PD-L1 staining patterns and neoadjuvant chemotherapy response in TNBC patients

From: Clinical impact of PD-L1 expression in triple-negative breast cancer patients with residual tumor burden after neoadjuvant chemotherapy

PD-L1 staining

N = 50

Class I and II (n = 22)

Class III (n = 27)

P value

Tumoral PD-L1 ≥ %1

25 (50 %)

11

14

0.999

TILs PD-L1 ≥ %1

23 (46 %)

14

10

0.064*

Tumoral and/or TILs PD-L1 ≥ %1

29 (58%)

14

15

0.771

Tumoral PD-L1 ≥ %5

16

8

8

0.761

TILs PD-L1 ≥ %5

21

11

10

0.398

Tumoral and/or TILs PD-L1 ≥ %5

23

12

11

0.396

Tumoral PD-L1 ≥ %10

13

7

6

0.525

TILs PD-L1 ≥ %10

15

8

7

0.538

Tumoral and/or TILs PD-L1 ≥ %10

19

10

9

0.556

Tumoral PD-L1 ≥ %20

7

4

3

0.685

TILs PD-L1 ≥ %20

6

2

4

0.678

Tumoral and/or TILs PD-L1 ≥ %20

9

4

5

0.999

  1. Tumor Infiltrating (stromal) lymphocytes (=TILs)