Fig. 8

Circ_0018289 silencing weakened tumor growth in vivo. A Growth curves of the xenograft tumors derived from subcutaneous injections into the nude mice of sh-circ_0018289-transduced or sh-NC-infected SiHa cells (n = 6 per group). Representative images and average weight (B), circ_0018289 expression by qRT-PCR analysis (C), miR-183-5p expression by qRT-PCR analysis (D), TMED5 mRNA level by qRT-PCR analysis (E), TMED5 protein level by western blot (F), and Ki67 level by immunohistochemistry (G) of the xenograft tumors at day 35 formed by sh-circ_0018289-transduced or sh-NC-infected SiHa cells (n = 6 per group). *P < 0.05