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Table 5 Univariate and multivariate analysis of the prognostic factors for recurrence-free survival of patients after PS matching

From: Prognostic value of Onodera’s nutritional index for intermediate- and high-risk gastrointestinal stromal tumors treated with or without tyrosine kinase inhibitors

Characteristics

Univariate analysis

Multivariate analysis

HR(95% CI)

P value

HR(95% CI)

P value

Age/year

 

0.023

 

0.008

  ≤ 60

1

 

1

 

  > 60

1.910(1.095–3.333)

 

2.175(1.226–3.859)

 

Gender

 

0.064

  

 Male

1

   

 Female

0.533(0.331–1.120)

   

GI bleeding

 

0.337

  

 Yes

1

   

 No

1.307(0.756–2.261)

   

Primary site

 

0.007

 

0.864

 Gastric

1

 

1

 

 Non-gastric

2.116(1.228–3.645)

 

1.066(0.560–2.029)

 

Tumor size

 

0.002

 

0.003

  ≤ 5.0 cm

1

 

1

 

  > 5.0 cm

1.962(1.254–2.848)

 

1.758(1.067–3.759)

 

Predominant cell type

 

0.419

  

 Spindle

1

   

 Epithelioid

0.765(0.263–3.376)

   

 Mixed

0.735(0.363–3.289)

   

Mitotic index

 

 < 0.001

 

0.002

  ≤ 5 per 50 HPFs

1

 

1

 

 6–10 per 50 HPFs

1.524(1.186–2.654)

 

1.387(1.084–2.368)

 

  > 10 per 50 HPFs

2.098(1.522–2.890)

 

1.811(1.247–2.629)

 

Tumor rupture

 

0.097

  

 No

1

   

 Yes

1.801(0.711–4.563)

   

NIH risk classification

 

 < 0.001

 

0.024

 Intermediate risk

1

 

1

 

 High risk

4.943(2.479–9.854)

 

2.640(1.140–6.115)

 

Ki-67 index

 

0.181

  

  ≤ 5

1

   

 6–10

1.128(0.581–3.835)

   

  > 10

1.045(0.854–4.185)

   

NLR

 

0.002

 

0.031

  < 5.1

1

 

1

 

  ≥ 5.1

1.552(1.180–2.041)

 

1.878 (1.060–3.327)

 

PLR

 

0.004

 

0.407

  < 98.6

1

 

1

 

  ≥ 98.6

1.453(1.126–1.875)

 

1.262(0.727–2.191)

 

OPNI

 

0.045

 

0.009

  < 42.6

1

 

1

 

  ≥ 42.6

0.409(0.170–0.980)

 

0.592 (0.400–0.875)