Fig. 1

Differential expression of data between two sets of samples. Principal component analysis plot of gene expression data showing the first two principal components in GSE9348 (a) and GSE11024 (d). Volcano plot of the differential expression of genes in GSE9348 (b). Principal component analysis plot of the gene expression data showing the first two principal components in GSE11024 (e), respectively. Hierarchical clustering heatmap for GSE9348 (c) and GSE11024 (f), DEGs screened on the basis of a fold change > 2.0 and a corrected P value of < 0.05. (g) Upsetplot showing the number of DEGs in CRC tissues compared to that of normal colorectal tissues