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Table 4 Adverse reactions in both groups of patients (n = 82)

From: Postoperative oxaliplatin-based hyperthermic intraperitoneal chemotherapy: an effective and safe palliative treatment option for colorectal cancer with peritoneal metastasis

Adverse event (<30 days)

HIPEC (n = 37)

Non-HIPEC (n = 45)

P

Nausea/vomiting, n (%)

13 (35.1)

15 (33.3)

0.864

Diarrhea, n (%)

17 (45.9)

22 (48.9)

0.791

Fever, n (%)

12 (32.4)

10 (22.2)

0.299

Neutrophil count decreased, n (%)

12 (32.4)

4 (8.9)

0.007

Aminotransferase increased, n (%)

6 (16.2)

3 (6.7)

0.287

Creatinine increased, n (%)

9 (24.3)

6 (13.3)

0.200

Peripheral neurotoxicity, n (%)

9 (24.3)

2 (4.4)

0.019