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Table 3 Clinicopathological characteristics of patients stratified by post-CRT LCR

From: Lymphocyte to C-reactive protein ratio predicts long-term outcomes for patients with lower rectal cancer

Characteristic

LCR low

(n = 24)

LCR high

(n = 24)

P value

Age (years)

67 ± 13

64 ± 9

0.36

Gender (male/female)

17/7

15/9

0.54

WBC (/μL)

5391 ± 1652

4441 ± 1127

0.06

TLC (/μL)

730 ± 460

971 ± 347

< 0.05

Alb (mg/dL)

3.4 ± 0.5

3.9 ± 0.4

0.91

CRP (mg/dL)

1.10 ± 1.60

0.26 ± 0.71

< 0.05

Pre-CRT LCR

9006 ± 9368

23322 ± 13945

< 0.05

Tumor characteristic

 Differentiation (tub1/tub2/other)

9/14/1

10/13/1

0.41

 CEA (</≥ 5 ng/mL)

18/6

16/8

0.53

 CA19-9 (</≥ 37 IU/mL)

20/4

20/4

1.00

 Pre-CRT stage (I/II/II)

1/3/15

2/8/13

0.20

Treatment

 Chemotherapy (S-1/UFT/5FU)

12/9/3

17/2/5

0.05

 Surgery (LAR/ISR/APR/local)

9/3/11/1

9/7/7/1

0.47

Pathological response (grade 2/≥ 2)

16/8

16/8

1.00

  1. WBC white blood cell, TLC total lymphocyte count, Alb albumin, CRP C-reactive protein, CEA carcinoembryonic antigen, LCR lymphocyte-CRP ratio, tub1 well-differentiated tubular adenocarcinoma, tub2 moderately differentiated tubular adenocarcinoma, S-1 tegafur-gimeracil-oteracil, UFT tegafur-uracil, 5-FU 5-fluorouracil, CRT chemo-radiotherapy, LAR low anterior resection, ISR intersphincteric resection, APR abdominoperineal resection