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Table 2 Clinicopathological characteristics of patients stratified by pre-CRT LCR

From: Lymphocyte to C-reactive protein ratio predicts long-term outcomes for patients with lower rectal cancer

Characteristic

LCR low

(n = 24)

LCR high

(n = 24)

P value

Age (years)

66 ± 13

65 ± 10

0.45

Gender (male/female)

16/8

16/8

1.00

WBC (/μL)

7266

6299

0.13

TLC (/μL)

1451 ± 640

1803 ± 502

0.07

Alb (mg/dL)

3.8 ± 0.5

3.9 ± 0.5

0.58

CRP (mg/dL)

1.23 ± 2.47

0.07 ± 0.02

< 0.05

Tumor characteristic

 Differentiation (tub1/tub2/other)

13/7/4

16/4/4

0.53

 CEA (</≥ 5 ng/mL)

16/8

18/6

1.00

 CA19-9 (</≥ 37 IU/mL)

20/4

20/4

0.09

 Pre-CRT stage (I/II/III)

1/3/16

2/8/12

0.17

Treatment

 Chemotherapy (S-1/UFT/5FU)

13/7/4

16/4/4

0.57

 Surgery (LAR/ISR/APR/local)

7/4/13/0

11/6/5/2

0.07

Pathological response (grade 2/> 2)

17/7

15/9

0.53

  1. Patients were stratified using the median LCR. WBC white blood cell, TLC total lymphocyte count, Alb albumin, CRP C-reactive protein, CEA carcinoembryonic antigen, LCR lymphocyte-CRP ratio, tub1 well-differentiated tubular adenocarcinoma, tub2 moderately differentiated tubular adenocarcinoma, S-1 tegafur-gimeracil-oteracil, UFT tegafur-uracil, 5-FU 5-fluorouracil, CRT chemo-radiotherapy, LAR low anterior resection, ISR intersphincteric resection, APR abdominoperineal resection