Table 9 Relationship between mutation of PIK3CA gene in exon E9 and clinical parameters
|  | Clinical parameters | No. | PIK3CA-E9 | Positive rate (%) | χ2 | p value | |
|---|---|---|---|---|---|---|---|
Wild type | Mutant type | ||||||
Age | ≤60 | 112 | 82 | 3 | 2.68 | 1.087 | 0.581 |
>60 | 109 | 79 | 1 | 0.92 | |||
Gender | Male | 114 | 82 | 4 | 3.51 | 3.838 | 0.147 |
Female | 107 | 79 | 0 | 0 | |||
Sample type | Tissue sample | 194 | 139 | 2 | 1.03 | 13.773 | 0.008 |
Whole blood sample | 22 | 18 | 1 | 4.55 | |||
Whole blood + tissue sample | 5 | 4 | 1 | 20.00 | |||
Pathological type | Squamous cell carcinoma | 15 | 10 | 2 | 13.33 | 13.353 | 0.038 |
Adenocarcinoma | 155 | 112 | 1 | 0.65 | |||
Adenosquamous carcinoma | 7 | 5 | 0 | 0 | |||
Staging | Stage IA | 22 | 16 | 0 | 0 | 10.663 | 0.712 |
Stage IB | 51 | 36 | 1 | 1.96 | |||
Stage IIA | 8 | 6 | 0 | 0 | |||
Stage IIB | 9 | 7 | 1 | 11.11 | |||
Stage IIIA | 23 | 16 | 0 | 0 | |||
Stage IIIB | 5 | 4 | 0 | 0 | |||
Stage IV | 33 | 28 | 1 | 3.03 | |||
Treatment | Surgery | 67 | 52 | 0 | 0 | 5.112 | 0.530 |
Chemotherapy | 37 | 24 | 2 | 5.41 | |||
Surgery + chemotherapy | 66 | 49 | 1 | 1.52 | |||