Table 3 Relationship between mutation of EGFR gene in exon E19 and clinical parameters
|  | Clinical parameters | No. | EGFR-E19 | Positive rate (%) | χ2 | p value | |
|---|---|---|---|---|---|---|---|
Wild type | Mutant type | ||||||
Age | ≤60 | 112 | 85 | 24 | 21.43 | 2.241 | 0.326 |
>60 | 109 | 91 | 15 | 13.76 | |||
Gender | Male | 114 | 96 | 14 | 12.28 | 5.007 | 0.082 |
Female | 107 | 80 | 25 | 23.36 | |||
Sample type | Tissue sample | 194 | 155 | 34 | 17.53 | 2.020 | 0.732 |
Whole blood sample | 22 | 16 | 5 | 22.73 | |||
Whole blood + tissue sample | 5 | 5 | 0 | 0 | |||
Pathological type | Squamous cell carcinoma | 15 | 14 | 0 | 0 | 10.285 | 0.113 |
Adenocarcinoma | 155 | 125 | 28 | 18.06 | |||
Adenosquamous carcinoma | 7 | 4 | 2 | 28.57 | |||
Staging | Stage IA | 22 | 18 | 4 | 18.18 | 20.438 | 0.117 |
Stage IB | 51 | 38 | 13 | 25.49 | |||
Stage IIA | 8 | 8 | 0 | 0 | |||
Stage IIB | 9 | 7 | 1 | 11.11 | |||
Stage IIIA | 23 | 19 | 2 | 8.70 | |||
Stage IIIB | 5 | 4 | 0 | 0 | |||
Stage IV | 33 | 28 | 5 | 15.15 | |||
Treatment | Surgery | 67 | 52 | 14 | 20.90 | 3.313 | 0.769 |
Chemotherapy | 37 | 31 | 5 | 13.51 | |||
Surgery + chemotherapy | 66 | 54 | 9 | 13.64 | |||