Table 2 Relationship between mutation of EGFR gene in exon E18 and clinical parameters
|  | Clinical parameters | No. | EGFR-E18 | Positive rate (%) | χ2 | p value | |
|---|---|---|---|---|---|---|---|
Wild type | Mutant type | ||||||
Age | ≤60 | 112 | 93 | 1 | 0.89 | 4.067 | 0.131 |
>60 | 109 | 95 | 4 | 3.67 | |||
Gender | Male | 114 | 97 | 1 | 0.88 | 2.344 | 0.310 |
Female | 107 | 91 | 4 | 3.74 | |||
Sample type | Tissue sample | 194 | 178 | 5 | 2.58 | 73.377 | <0.001 |
Whole blood sample | 22 | 7 | 0 | 0 | |||
Whole blood + tissue sample | 5 | 3 | 0 | 0 | |||
Pathological type | Squamous cell carcinoma | 15 | 10 | 0 | 0 | 16.489 | 0.011 |
Adenocarcinoma | 155 | 138 | 4 | 2.58 | |||
Adenosquamous carcinoma | 7 | 5 | 1 | 14.29 | |||
Staging | Stage IA | 22 | 19 | 3 | 13.64 | 40.276 | <0.001 |
Stage IB | 51 | 48 | 1 | 1.96 | |||
Stage IIA | 8 | 7 | 1 | 12.50 | |||
Stage IIB | 9 | 8 | 0 | 0 | |||
Stage IIIA | 23 | 20 | 0 | 0 | |||
Stage IIIB | 5 | 2 | 0 | 0 | |||
Stage IV | 33 | 28 | 0 | 0 | |||
Treatment | Surgery | 67 | 61 | 4 | 5.97 | 20.081 | 0.003 |
Chemotherapy | 37 | 28 | 0 | 0 | |||
Surgery + chemotherapy | 66 | 59 | 1 | 1.52 | |||