First-line medical treatment | |||||
---|---|---|---|---|---|
Nephrectomy status | No surgical treatment | Cytoreductive nephrectomy | Surgery with curative intent | p value | |
Median OS (95% CI), months | |||||
No medical treatment | 3.5 (2.5–4.4) | 4.1 (3.0–5.2) | 50.6 (0.0–105.7) | < 0.001 | |
Chemotherapy | 7.3 (5.4–9.2) | 10.3 (3.4–17.3) | – | 0.92 | |
Interferon ± chemotherapy | 10.0 (7.3–12.7) | 18.6 (14.7–22.4) | 43.6 (0.0–116.8) | 0.002 | |
Targeted therapy | 10.6 (8.1–13.1) | 21.9 (16.8–27.0) | 57.2 (36.2–78.1) | < 0.001 |