Skip to main content

Table 1 Characteristics of included studies

From: Oncologic and long-term outcomes of enhanced recovery after surgery in cancer surgeries — a systematic review

Author

Year

Study design

Surgery

Groups

Patient age (year)

Outcomes

NOS/Jadad score*

Non-ERAS vs ERAS

 Oakley et al. [10]

2016

Retrospective cohort

Esophagi-gastric resection

Non-ERAS (n = 81)

ERAS (n = 66)

Median 78.8

Median 78.5

OS

8

 Pang et al. [11]

2018

Prospective cohort

Radical cystectomy

Non-ERAS (n = 393)

ERAS (n = 60)

Median 66

Median 71

OS

CSS

7

 Ziegelmueller et al. [12]

2019

Prospective randomized

Radical cystectomy

Non-ERAS (n = 38)

ERAS (n = 60)

Median 67.5

Median 70

OS

CSS

4*

 Ye [13]

2017

Prospective randomized

Radical gastrectomy

Non-ERAS (n = 38)

ERAS (n = 47)

Mean 43.2

Mean 45.2

OS

4*

 Yang et al. [14]

2020

Retrospective cohort

Radical gastrectomy

Non-ERAS (n = 521)

ERAS (n = 521)

Mean 63

OS

8

 Liu et al. [15]

2020

Randomized control trial

Craniotomy

Non-ERAS (n = 29)

ERAS (n = 36)

18–65

Life quality

6*

 Passeri et al. [16]

2020

Prospective cohort

Pancreatico-duodenectomy

Non-ERAS (n = 86)

ERAS (n = 86)

Median 67

OS

DFS

6

 Day et al. [17]

2015

Prospective cohort

Hepatectomy

Non-ERAS (n = 43)

ERAS (n = 75)

Median 60

Median 59

Failure to RIOT

Days to RIOT

8

 Lohsiriwat [18]

2014

Prospective cohort

Colorectal cancer resection

Non-ERAS (n = 40)

ERAS (n = 20)

Mean 62

Mean 57.6

Days to RIOT

7

 Hassinger et al. [19]

2019

Retrospective cohort

Colorectal cancer resection

Non-ERAS (n = 174)

ERAS (n = 189)

Median 61.1

Median 62.4

Rate of on time to RIOT

8

 Nelson et al. [20]

2019

Prospective cohort

Lung resection

Non-ERAS (n = 230)

ERAS (n = 92)

Median 66

Days to RIOT

Rate of completing RIOT

7

 Li et al. [21]

2020

Prospective cohort

Pancreatico-duodenectomy

Non-ERAS (n = 141)

ERAS (n = 203)

Median 58.2

Median 58.9

Days to RIOT

7

 Wang et al. [29]

2021

Retrospective cohort

Colorectal cancer resection

Non-ERAS (1) (n = 142)

ERAS (1) (n = 125)

Non-ERAS (2) (n = 138)

ERAS (2) (n = 137)

Median 57.65

Median 56.22

Median 58.45

Median 57.18

OS; DFS

7

 Zhang et al. [30]

2021

Retrospective cohort

Hepatectomy

Non-ERAS (n = 463)

ERAS (n = 463)

Median 62.8

Median 63.2

OS; DFS

7

 Quiram et al. [31]

2019

Retrospective cohort

Rectal cancer resection

Non-ERAS (n = 280)

ERAS (n = 320)

Median 58.9

Median 58.2

OS; DFS; local recurrence; metastasis

7

 Zhu et al. [32]

2019

Retrospective cohort

Pancreatico-duodenectomy

Non-ERAS (n = 69)

ERAS (n = 64)

Median 64.1

Median 64.3

OS

6

 Tian et al. [33]

2020

Retrospective cohort

Gastrectomy

Non-ERAS (n = 365)

ERAS (n = 365)

Median 59.4

Median 59.5

OS; CSS

7

 Lohsiriwat et al. [34]

2021

Prospective cohort

Colorectal cancer resection

Non-ERAS (n = 279)

ERAS (n = 70)

Mean 63.1

Mean 62.1

OS

7

High adherence vs low adherence to ERAS

 Passeri et al. [16]

2020

Prospective cohort

Pancreatico-duodenectomy

High (n = 42)

Low (n = 44)

Median 67

OS; DFS

6

 Viannay et al. [22]

2019

Retrospective cohort

Colectomy

High (n = 52)

Low (n = 154)

Mean 68.2

Mean 71.8

OS; survival of metastasis

7

 Gustafsson et al. [23]

2016

Retrospective cohort

Colorectal resection

High (n = 273)

Low (n = 638)

Mean 68.7

Mean 69.6

Local recurrence; OS; CSS

7

 Pisarska et al. [24]

2019

Prospective cohort

Colorectal resection

High (n = 241)

Low (n = 109)

Mean 63.8

Mean 64.9

OS

7

 St-Amour et al. [25]

2020

Retrospective cohort

Surgery for liver and pancreatic cancer

High (n = 42)

Low (n = 91)

Median 67

Days to RIOT in young patients; DFS in young patients

6

 Rubinkiewicz et al. [26]

2020

Retrospective cohort

Gastrectomy

High (n = 34)

Low (n = 44)

Mean 61.1

Mean 61.3

OS

7

 Lohsiriwat et al. [34]

2021

Prospective cohort

Colorectal cancer resection

High (n = 232)

Low (n = 88)

Mean 62.5

Mean 65.1

OS

7

Alteration of single item within ERAS protocol

 Curtis et al. [27]

2018

Prospective cohort

Colorectal resection

Laparoscopy surgery (n = 383)

Open surgery (n = 373)

Unclear

OS

7

 Wang et al. [29]

2021

Retrospective cohort

Colorectal cancer resection

Laparoscopy (n = 125)

Open surgery (n = 137)

Mean 56.2

Mean 57.1

OS; DFS

7

 Asklid et al. [28]

2017

Prospective cohort

Colorectal resection

Restrictive fluid therapy (n = 145)

Liberal fluid therapy (n = 753)

Mean 69.3

Local recurrence; OD; CSD

7

 Kato et al. [35]

2021

Retrospective cohort

Rectosigmoid resection

Early oral feeding (n = 106)

Conventional oral feeding (n = 95)

Median 60

Median 62

Days to RIOT

6

  1. RIOT return to intended oncologic therapy, OS overall survival, CSS cancer-specific survival, DFS disease-free survival, OD overall death, CSD cancer-specific death
  2. *Study evaluated by Jadad score