Table 2 Univariate analysis and multivariate analysis of factors associated with OS using a Cox regression model for patients underwent CRS in our center. Statistically significant P values are presented in bold-italics. P values that are not statistically significant are presented in in italics

Tumor deposits

 None

 Present

1.131 (0.589–2.172)

P=0.711

 Unknown

0.355 (0.081–1.556)

P=0.169

Perineural invasion

 None

 Present

1.233 (0.613–2.480)

P=0.556

 Unknown

0.375 (0.114–1.234)

P=0.107

Scope Reg LN Sur

 None

 Present

1.785 (0.781–4.079)

P=0.169

 Unknown

0.515 (0.105–2.535)

P=0.414

Scope Reg LN Sur (Number)

 <4

 ≥4

1.536 (0.792–2.978)

P=0.204

 Unknown

0.394 (0.090–1.724)

P=0.216

HIPEC

 No

 Yes

0.868 (0.479–1.573)

P=0.641

Metastatic tumor size

 ≤15cm

 >15cm

2.536 (1.174–5.480)

P=0.018

 Unknown

0.711 (0.167–3.024)

P=0.644

Number of OM

 Unilateral

 Bilateral

1.956 (0.965–3.967)

P=0.063

 Unknown

1.779 (0.394–8.021)

P=0.454

PM

 No

 Yes

2.295 (1.170–4.503)

P=0.016

PCI

 ≤10

 >10

2.807 (1.421–5.544)

P=0.003

CA125

 ≤ 40 kU/L

 >40 kU/L

1.212 (0.603–2.436)

P=0.589

 unknown

1.012 (0.411–2.491)

P=0.979

CEA

 ≤30 mg/L

 >30 mg/L

0.899 (0.437–1.852)

P=0.773

 unknown

0.728 (0.276–1.920)

P=0.521

CA199

 ≤60 kU/L

 >60 kU/L

0.837 (0.397–1.765)

P=0.641

 unknown

0.713 (0.271–1.876)

P=0.494

CC

 0

 1

7.412 (2.170–25.317)

P=0.001

7.412(2.170-25.317)

P=0.001

 2

4.827 (2.235–10.422)

P<0.001

4.827(2.235-10.422)

P<0.001

 3

143.854 (8.430–2454.725)

P=0.001

143.854(8.430-2454.725)

P=0.001

CC

 0–1

 >1

3.782 (1.873–7.637)

P<0.001

3.782(1.873-7.637)

P<0.001