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Table 3 Univariate analysis of tumor-related variables for symptomatic anastomotic leakage

From: Risk factors of symptomatic anastomotic leakage and its impacts on a long-term survival after laparoscopic low anterior resection for rectal cancer: a retrospective single-center study

Variables

AL (−) (N=290)

AL (+) (N=8)

χ2

P value

Pathology type of tumor

  

0.405

0.817

 Adenocarcinoma

276 (95.2)

8 (100)

  

 Mucinous carcinoma

11 (3.8)

0 (0)

  

 Signet-ring cell

3 (1.0)

0 (0)

  

Size of tumor(cm)

  

0.576

0.448

 ≤5

246 (84.8)

6 (75)

  

 >5

44 (15.2)

2 (25)

  

Tumor differentiation

  

2.410

0.661

 Well

19(6.6)

0 (0)

  

 Moderate

224 (77.2)

6 (75)

  

 Poor

 Well-moderate

9 (3.1)

7 (2.4)

0 (0)

0 (0)

  

 Moderate-poor

31 (10.7)

2 (25)

  

Tumor type

  

3.526

0.172

 Ulcer

182 (62.8)

7 (87.5)

  

 Uplift

88 (30.3)

0 (0)

  

Infiltrating

20 (6.9)

1 (12.5)

  

Tumor infiltrating

  

2.570

0.766

 1/4 circle

38 (12.8)

2 (25)

  

 1/3 circle

79 (26.5)

1 (12.5)

  

 1/2 circle

68 (22.8)

2 (25)

  

 2/3 circle

48 (16.1)

2 (25)

  

 3/4 circle

27 (9.1)

0 (0)

  

Full circle

30 (10.1)

1 (12.5)

  

Vascular invasion

  

0.213

0.644

 No

235 (81)

7 (87.5)

  

 Yes

55 (19)

1 (12.5)

  

Nerve invasion

  

0.655

0.418

 No

268 (92.4)

8 (100)

  

 Yes

22 (7.6)

0 (0)

  

Pathological tumor(T)category

  

15.357

0.004†

 T0

5 (1.7)

0 (0)

  

 T1

21(7.3)

0 (0)

  

 T2

55 (19)

6 (75)

  

 T3

163 (56.4)

1 (12.5)

  

 T4

45 (15.6)

1 (12.5)

  

Pathological node(N)category

  

1.945

0.584

 N0

162 (55.9)

6 (75)

  

 N1

76 (26.2)

2 (25)

  

 N2

46 (15.9)

0 (0)

  

 N3

6 (2.1)

0 (0)

  

Metastasis

  

0.345

0.557

 M0

278 (95.9)

8 (100)

  

 M1

12 (4.1)

0 (0)

  

Cancerous node

  

1.305

0.253

 No

278 (95.9)

7 (87.5)

  

 Yes

12 (4.1)

1 (12.5)

  
  1. AL anastomotic leakage, χ2 chi-square test
  2. †p<0.1