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Table 1 Univariate analysis of patient-related variables with symptomatic anastomotic leakage

From: Risk factors of symptomatic anastomotic leakage and its impacts on a long-term survival after laparoscopic low anterior resection for rectal cancer: a retrospective single-center study

Variables

AL (−) (N=290)

AL (+) (N=8)

χ2

P value

Gender

  

1.120

0.290

 Male

163 (56.2)

6 (75)

  

 Female

127 (43.8)

2 (25)

  

Age (years)

  

3.907

0.048†

 ≤ 65

194 (66.9)

8 (100)

  

 >65

96 (33.1)

0 (0)

  

ASA category

  

1.290

0.525

 I

40 (13.8)

0 (0)

  

 II

222 (76.6)

7 (87.5)

  

 III

28 (9.6)

1 (12.5)

  

Smoking

  

0.148

0.701

 No

199 (68.6)

6 (75)

  

 Yes

91 (31.4)

2 (25)

  

Alcohol consumption

  

2.408

0.121

 No

242 (83.4)

5 (62.5)

  

 Yes

48 (16.6)

3 (37.5)

  

Previous history of abdominal surgery

  

0.175

0.676

 No

237 (81.7)

7 (87.5)

  

 Yes

53 (18.3)

1 (12.5)

  

Preoperative intestinal obstruction

  

0.886

0.346

 No

261 (90)

8 (100)

  

 Yes

29 (10)

0 (0)

  

Hypertension

  

0.796

0.372

 No

213 (73.4)

7 (87.5)

  

 Yes

77 (26.6)

1 (12.5)

  

Diabetes

  

0.989

0.320

 No

258 (89.0)

8 (100)

  

 Yes

32 (11.0)

0 (0)

  

BMI (kg/m2)

  

2.352

0.309

 ≤18

17 (5.8)

0 (0)

  

18–25

140 (48.3)

6 (75)

  

 ≥ 25

133 (45.9)

2 (25)

  

Neoadjuvant therapy

  

2.784

0.095†

 No

245 (84.5)

5 (62.5)

  

 Yes

45 (15.5)

3 (37.5)

  

Pulmonary insufficiency

  

2.571

0.109

 No

219 (75.5)

8 (100)

  

 Yes

71 (24.5)

0 (0)

  

Preoperative hemoglobin(g/L)

  

0.898

0.343

 <120

67 (23.1)

3 (37.5)

  

 ≥120

223 (76.9)

5 (62.5)

  

Preoperative white blood cell

  

0.591

0.442

 4000–12000

270 (93.1)

8 (100)

  

 <4000 or >12000

20 (6.9)

0 (0)

  

Preoperative serum albumin (g/L)

  

0.440

0.507

 <35

19 (6.6)

1 (12.5)

  

 ≥35

271 (93.4)

7 (87.5)

  

Preoperative CEA (ng/ml)

  

0.732

0.392

 <5

174 (60)

6 (75)

  

 ≥5

116 (40)

2 (25)

  
  1. AL anastomotic leakage, ASA American Society of Anesthesiologists, BMI body mass index, CEA carcinoembryonic antigen, χ2 chi-square test
  2. †p<0.1