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Table 5 Univariate and multivariate logistic regression analysis on UI level for the presence of CLNM in PTC patients

From: Low urinary iodine is a protective factor of central lymph node metastasis in papillary thyroid cancer: a cross-sectional study

Urinary iodine status (μg/L)

Univariate

Multivariatec

OR

95% CI

P value

OR

95% CI

P value

Total patientsa

≤ 99 (n = 102)

0.59

0.36–0.98

0.043

0.71

0.41–1.23

0.221

100–199 (n = 164)

Reference

  

Reference

  

≥ 200 (n = 93)

0.98

0.59–1.63

0.934

0.99

0.59–1.83

0.98

PTC ≥ 1 cma

≤ 99 (n = 39)

0.4

0.17–0.91

0.031

0.51

0.20–1.30

0.161

100–199 (n = 56)

Reference

  

Reference

  

≥ 200 (n = 30)

1.03

0.41–2.69

0.956

1.26

0.44–3.73

0.674

PTC < 1 cma

≤ 99 (n = 63)

0.7

0.36–1.33

0.281

0.73

0.35–1.48

0.381

100–199 (n = 108)

Reference

  

Reference

  

≥ 200 (n = 63)

0.98

0.52–1.85

0.96

1.09

0.55–2.15

0.815

Total patientsb

≤ 109 (n = 135)

0.44

0.26–0.72

0.001

0.53

0.31–0.91

0.021

110–189 (n = 120)

Reference

  

Reference

  

≥ 190 (n = 104)

0.68

0.40–1.15

0.154

0.71

0.41–1.29

0.281

PTC ≥ 1 cmb

≤ 109 (n = 50)

0.38

0.16–0.89

0.028

0.59

0.22–1.58

0.294

110–189 (n = 42)

Reference

  

Reference

  

≥ 190 (n = 33)

0.9

0.34–2.40

0.826

1.33

0.45–4.06

0.608

PTC < 1 cmb

≤ 109 (n = 85)

0.44

0.23–0.83

0.012

0.43

0.21–0.87

0.019

110–189 (n = 78)

Reference

  

Reference

  

≥ 190 (n = 71)

0.61

0.32–1.18

0.143

0.65

0.32–1.33

0.242

  1. aIodine insufficient, adequate, and above requirements (including excessive) were defined as ≤ 99 μg/L, 100–199 μg/L, and ≥ 200 μg/L
  2. bIodine insufficient, adequate, and above requirements (including excessive) were defined as ≤ 109 μg/L, 110–189 μg/L, and ≥ 190 μg/L
  3. cAdjusted for age, sex, multifocality, tumor size, and variant subtype