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Table 3 Correlation of UI/U-Cr and clinicopathological features of PTC

From: Low urinary iodine is a protective factor of central lymph node metastasis in papillary thyroid cancer: a cross-sectional study

Variables

Before PSM

After PSM

n

UI/U-Cr, μg/g

P value

n

UI/U-Cr, μg/g

P value

Low

High

Low

High

n = 176

n = 183

n = 118

n = 118

Age

 ≥ 45

155 (43.2)

60 (16.7)

95 (26.5)

0.001

105 (44.5)

49 (20.8)

56 (23.7)

0.359

 < 45

204 (56.8)

116 (32.3)

88 (24.5)

131 (55.5)

69 (29.2)

62 (26.3)

Sex

 Male

104 (29)

63 (17.5)

41 (11.4)

0.005

59 (25)

27 (11.4)

32 (13.6)

0.452

 Female

255 (71)

113 (31.5)

142 (39.6)

177 (75)

91 (38.6)

86 (36.4)

BMI, kg/m2

 ≥ 24

205 (57.1)

105 (29.2)

100 (27.9)

0.337

130 (55.1)

67 (28.4)

63 (26.7)

0.601

 < 24

154 (42.9)

71 (19.8)

83 (23.1)

106 (44.9)

51 (21.6)

55 (23.3)

Diabetes

 Yes

16 (4.5)

3 (0.8)

13 (3.6)

0.013

10 (4.2)

2 (0.8)

8 (3.4)

0.102

 No

343 (95.5)

173 (48.2)

170 (47.4)

226 (95.8)

116 (49.2)

110 (46.6)

Hypertension

 Yes

63 (17.5)

29 (8.1)

34 (9.5)

0.601

41 (17.4)

19 (8.1)

22 (9.3)

0.606

 No

296 (82.5)

147 (40.9)

149 (41.5)

195 (82.6)

99 (41.9)

96 (40.7)

Tobacco use

 Yes

38 (10.6)

21 (5.8)

17 (4.7)

0.416

25 (10.6)

12 (5.1)

13 (5.5)

0.832

 No

321 (89.4)

155 (43.2)

166 (46.2)

211 (89.4)

106 (44.9)

105 (44.5)

Tumor size

 ≥ 1 cm

125 (34.8)

55 (15.3)

70 (19.5)

0.164

88 (37.3)

40 (16.9)

48 (20.3)

0.282

 < 1 cm

234 (65.2)

121 (33.7)

113 (31.5)

148 (62.7)

78 (33.1)

70 (29.7)

Multifocality

 Yes

131 (36.5)

57 (15.9)

74 (20.6)

0.113

93 (39.4)

43 (18.2)

50 (21.2)

0.351

 No

228 (63.5)

119 (33.1)

109 (30.4)

143 (60.6)

75 (31.8)

68 (28.8)

Capsular invasion

 Yes

253 (70.5)

123 (34.3)

130 (36.2)

0.811

162 (68.6)

83 (35.2)

79 (33.5)

0.575

 No

106 (29.5)

53 (14.8)

53 (14.8)

74 (31.4)

35 (14.8)

39 (16.5)

Nodular goiter

 Yes

99 (27.6)

50 (13.9)

49 (13.6)

0.729

66 (28)

34 (14.4)

32 (13.6)

0.772

 No

260 (72.4)

126 (35.1)

134 (37.3)

170 (72)

84 (35.6)

86 (36.4)

Chronic thyroiditis

 Yes

94 (26.2)

40 (11.1)

54 (15)

0.144

63 (26.7)

28 (11.9)

35 (14.8)

0.303

 No

265 (73.8)

136 (37.9)

129 (35.9)

173 (73.3)

90 (38.1)

83 (35.2)

Thyroid adenoma

 Yes

5 (1.4)

4 (1.1)

1 (0.3)

0.207

3 (1.3)

2 (0.8)

1 (0.4)

1

 No

354 (98.6)

172 (47.9)

182 (50.7)

233 (98.7)

116 (49.2)

117 (49.6)

Variant subtype

 Classic

261 (72.7)

136 (37.9)

125 (34.8)

0.054

164 (69.5)

84 (35.6)

80 (33.9)

0.432

 Follicular

65 (18.1)

30 (8.4)

35 (9.7)

48 (20.3)

25 (10.6)

23 (9.7)

 Classic and follicular (multiple foci)

33 (9.2)

10 (2.8)

23 (6.4)

24 (10.2)

9 (3.8)

15 (6.4)

CLNM

 Yes

166 (46.2)

80 (22.3)

86 (24)

0.77

106 (44.9)

49 (20.8)

57 (24.2)

0.295

 No

193 (53.8)

96 (26.7)

97 (27)

130 (55.1)

69 (29.2)

61 (25.8)