Low urinary iodine is a protective factor of central lymph node metastasis in papillary thyroid cancer: a cross-sectional study

Table 1 Comparisons of UI and UI/U-Cr between different clinicopathological status of PTC patients

Variables	n	UI, μg/L	P value	UI/Cr, μg/g	P value
Age
≥ 45	155	131 (87–198)	0.266	97 (75–138)	< 0.001
< 45	204	147 (97–210)	0.266	80 (56–124)	< 0.001
Sex
Male	104	146 (103–201)	0.353	76 (51–111)	< 0.001
Female	255	140 (86–208)	0.353	95 (70–142)	< 0.001
BMI, kg/m²
≥ 24	205	132 (90–197)	0.261	86 (62–124)	0.202
< 24	154	152 (96–218)	0.261	93 (67–137)	0.202
Tobacco use
Yes	38	136 (94–218)	0.782	86 (54–123)	0.15
No	321	140 (87–196)	0.782	91 (64–132)	0.15
Tumor size
≥ 1 cm	125	139 (86–197)	0.711	95 (61–132)	0.602
< 1 cm	234	142 (94–209)	0.711	87 (63–127)	0.602
Multifocality
Yes	131	148 (96–208)	0.53	95 (68–136)	0.137
No	228	136 (90–205)	0.53	86 (61–124)	0.137
Capsular invasion
Yes	253	139 (84–195)	0.066	90 (61–131)	0.65
No	106	148 (104–219)	0.066	90 (64–127)	0.65
Pathological subtype
Classic variant	261	142 (94–209)	0.484	86 (61–131)	0.021
Follicular variant	65	126 (77–197)		90 (62–124)
Classic and follicular variant	33	166 (87–215)		102 (85–143)
CLNM
Yes	166	152 (105–215)	0.028	94 (61–141)	0.523
No	193	126 (84–197)	0.028	90 (64–123)	0.523

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