From: Histiocytic pleural effusion: the strong clue to malignancy
Malignant PE | Parapneumonic effusion | Tuberculous pleurisy | Heart failure, liver cirrhosis, or renal failure | |
---|---|---|---|---|
Number | 102 (50.7) | 9 (4.5) | 9 (4.5) | 24 (11.9) |
Age (years) | 62.0 (52.0–74.0) | 71.0 (64.0–73.0) | 63.0 (54.0–79.0) | 64.5 (54.0–79.0) |
Sex | ||||
Male | 49 (48.0) | 5 (55.6) | 5 (55.6) | 17 (70.8) |
Female | 53 (52.0) | 4 (44.4) | 4 (44.4) | 7 (29.2) |
Smoking status | ||||
Non-smoker | 64 (62.7) | 4 (44.4) | 3 (33.3) | 9 (37.5) |
Current/ex-smoker | 8 (7.8)/30 (29.4) | 2 (22.2)/3 (33.3) | 2 (22.2)/4 (44.4) | 7 (29.2)/8 (33.3) |
Pleural fluid | ||||
RBC (/uL) | 3750 (740–27000) | 6240 (70–11,200) | 560 (250–3800) | 495 (180–7110) |
WBC (/uL) | 460 (200–1000) | 2500 (430–3680) | 570 (310–720) | 320 (105–560) |
Histiocyte (%) | 62.5 (55.0–70.0) | 66.0 (53.0–78.0) | 69.0 (62.0–74.0) | 63.0 (55.0–77.5) |
Neutrophil (%) | 5.0 (2.0–12.0) | 10.0 (3.0–12.0) | 5.0 (2.0–6.0) | 2.0 (1.0–6.5) |
Lymphocyte (%) | 16.5 (10.0–26.0) | 7.0 (1.0–11.0) | 19.0 (11.0–28.0) | 16.0 (10.0–29.5) |
Mesothelial cell (%) | 0.0 (0.0–2.0) | 0.0 (0.0–15.0) | 0.0 (0.0–1.0) | 0.5 (0.0–11.0) |
ADA (IU/L) | 24.7 (15.9–34.3) | 27.0 (17.7–38.0) | 71.4 (47.1–107.1) | 14.5 (9.4–19.3) |
Protein (g/dL) | 4.2 (3.4–4.6) | 4.3 (3.9–5.0) | 3.5 (2.9–3.7) | 2.8 (1.7–3.3) |
LDH (IU/L) | 305.0 (202.0–706.5) | 254.0 (184.0–361.0) | 207.0 (179.0–266.0) | 173.0 (138.0–219.0) |
Serum | ||||
Protein (g/dL) | 6.2 (5.6–6.6) | 6.4 (5.6–7.3) | 6.1 (6.0–6.6) | 6.3 (5.5–6.7) |
LDH (IU/L) | 317.0 (210.0–435.0) | 149.0 (128.0–212.0) | 331.0 (191.0–488.0) | 492.0 (277.0–685.0) |