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Table 5 Tumor responses between the mistletoe and non-mistletoe groups

From: Effect of mistletoe extract on tumor response in neoadjuvant chemoradiotherapy for rectal cancer: a cohort study

Variables

MG (n = 15)

NMG (n = 37)

P-value

pCR

  

0.044¶,**

 Yes

8 (53.3)

8 (21.6)

 

 No

7 (46.7)

29 (78.4)

 

TRG (AJCC)

  

0.024¶,**

 Good responder (0–1)

10 (66.7)

12 (32.4)

 

 Poor responder (2–3)

5 (33.3)

25 (67.6)

 

T downstaging

  

0.004¶,**

 Yes

13 (86.7)

16 (43.2)

 

 No

2 (13.3)

21 (56.8)

 

N downstaging

  

0.257

 Yes

14 (93.3)

29 (78.4)

 

 No

1 (6.7)

8 (21.6)

 

Overall TNM downstaging

  

0.040¶,**

 Yes

13 (86.7)

21 (56.8)

 

 No

2 (13.3)

16 (43.2)

 
  1. Data are presented as n (%)
  2. Chi-square test or Fisher’s exact test; **statistically significant (P < 0.05)
  3. MG, mistletoe group; NMG, non-mistletoe group; pCR, pathologic complete response; TRG, tumor regression grade; AJCC, American Joint Committee on Cancer; TNM, tumor–node–metastasis