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Table 3 Toxicity outcomes in the mistletoe and non-mistletoe groups

From: Effect of mistletoe extract on tumor response in neoadjuvant chemoradiotherapy for rectal cancer: a cohort study

Toxicity CTCAE P-value
MG (n = 15) NMG (n = 37)  
Grade 1 Grade 2 Grade 3 Grade 4 Grade 1 Grade 2 Grade 3 Grade 4
Neutropenia 0 0 0 0 0 1 (2.7) 0 0 > 0.99
Anemia 0 0 0 0 0 0 1 (2.7) 0 > 0.99
Thrombocytopenia 0 0 0 0 0 0 0 0
Nausea 4 (26.7) 0 0 0 6 (16.2) 0 0 0 0.448
Vomiting 1 (6.7) 0 0 0 0 0 0 0 0.288
Diarrhea 2 (13.3) 0 0 0 5 (13.5) 0 0 0 > 0.99
Constipation 0 0 0 0 4 (2.8) 0 0 0 0.311
Proctitis 9 (60.0) 0 0 0 10 (27.0) 0 0 0 0.054
Oral mucositis 0 0 0 0 1 (2.7) 0 0 0 > 0.99
Peripheral neuropathy 1 (6.7) 0 0 0 0 0 0 0 0.288
Pruritus 3 (20.0) 0 0 0 0 0 0 0 0.021
  1. Data are presented as n (%)
  2. Chi-square test or Fisher’s exact test
  3. CTCAE, Common Terminology Criteria for Adverse Events version 3.0; MG, mistletoe group; NMG, non-mistletoe group