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Table 2 ROC analysis of Tlen, Tdia, Tare, and Tvol in the differentiation of N stage in patients with colon cancer

From: Tumor size measured by multidetector CT in resectable colon cancer: correlation with regional lymph node metastasis and N stage

Tumor size

Cutoff

AUC (95% CI)

P value

Sensitivity

(95% CI)

Specificity

(95% CI)

Accuracy

(95% CI)

N0 VS N1-2

Tlen (cm)

5.20

0.82 (0.74~0.90)

< 0.001

71.2% (57.7~81.8%, 37/52)

81.5% (69.0~90.0%, 44/54)

76.4% (67.5~83.5%, 81/106)

Tdia (cm)

1.56

0.69 (0.58~0.79)

0.001

71.2% (57.7~81.8%, 37/52)

51.9% (38.9~64.6%, 28/54)

61.3% (51.8~70.1%, 65/106)

Tare (cm2)

9.47

0.79 (0.70~0.87)

< 0.001

84.6% (72.2~92.3%, 44/52)

61.1% (47.8~72.3%, 33/54)

72.6% (63.4~80.3%, 77/106)

Tvol (cm3)

38.00

0.83 (0.74~0.90)

< 0.001

69.2% (55.7~80.2%, 36/52)

83.3% (71.0~91.2%, 45/54)

76.4% (67.5~83.5%, 81/106)

N0 VS N1

Tlen (cm)

4.25

0.78 (0.68~0.88)

< 0.001

82.9% (66.9~92.3%, 29/35)

61.1% (47.8~73.0%, 33/54)

69.7% (59.4~78.3%, 62/89)

Tdia (cm)

1.49

0.63 (0.51~0.75)

0.041

74.3% (57.8~86.0%, 26/35)

48.1% (35.4~61.2%, 26/54)

58.4% (48.0~68.1%, 52/89)

Tare (cm2)

9.47

0.74 (0.64~0.84)

< 0.001

80.0% (63.8~90.2%, 28/35)

61.1% (47.8~73.0%, 33/54)

68.5% (58.3~77.3%, 61/89)

Tvol (cm3)

23.22

0.79 (0.70~0.88)

< 0.001

88.6% (73.5~96.1%, 31/35)

57.4% (44.2~69.7%, 31/54)

69.7% (59.4~78.3%, 62/89)

N0 VS N2

Tlen (cm)

5.20

0.89 (0.82~0.97)

< 0.001

94.1% (71.1~100%, 16/17)

81.5% (69.0~89.8%, 44/54)

84.5% (74.2~91.3%, 60/71)

Tdia (cm)

1.99

0.80 (0.70~0.91)

< 0.001

82.4% (58.2~94.6%, 14/17)

70.4% (57.1~80.9%, 38/54)

74.6% (63.4~83.4%, 53/71)

Tare (cm2)

13.41

0.89 (0.80~0.97)

< 0.001

82.4% (58.2~94.6%, 14/17)

83.3% (71.0~91.2%, 45/54)

83.1% (72.3~90.2%, 59/71)

Tvol (cm3)

38.40

0.92 (0.86~0.99)

< 0.001

94.1% (71.1~100%, 16/17)

83.3% (71.0~91.2%, 45/54)

85.6% (75.8~92.4%, 61/71)

N0-1 VS N2

Tlen (cm)

5.20

0.79 (0.70~0.88)

< 0.001

94.1% (71.1~100%, 16/17)

65.2% (54.8~74.3%, 58/89)

69.8% (60.5~77.8%, 74/106)

Tdia (cm)

2.00

0.76 (0.66~0.86)

0.001

82.4% (58.2~94.6%, 14/17)

67.4% (57.1~76.3%, 60/89)

69.8% (60.5~77.8%, 74/106)

Tare (cm2)

13.41

0.83 (0.72~0.93)

< 0.001

82.4% (58.2~94.6%, 14/17)

75.3% (65.3~85.2%, 67/89)

76.4% (67.5~83.5%, 81/106)

Tvol (cm3)

38.63

0.84 (0.76~0.93)

< 0.001

94.1% (71.1~100%, 16/17)

68.5% (58.3~77.3%, 61/89)

72.6% (63.4~80.3%, 77/106)

  1. Note: Tdia tumor maximum diameter, Tlen tumor length, Tare tumor maximum cross-sectional area, Tvol tumor volume, AUC the area under the ROC curve, CI confidence interval