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Table 2 Univariate and multivariate analyses for factors predicting response to chemotherapy

From: Serum IgG level is a predicting factor for the response to neoadjuvant chemotherapy in patients with esophageal squamous cell carcinoma

  

Univariate analysis

 

Multivariate analysis

 

Factor

Unfavorable/favorable

Odds ratio

95% CI

p value

Odds ratio

95% CI

p value

Age

>65/65≥

0.237

0.086–0.649

0.005

0.517

0.128–2.090

0.354

NAC regimen

FP/DSF

0.406

0.160–1.030

0.059

   

NAC cycles

1/2

9.12

2.720–30.600

<0.001

16.7

2.990–93.300

<0.001

Final T factor

T3-4/T0-2

1.6

0.652–3.950

0.304

   

Final N factor

N1-4/N0

0.568

0.229–1.410

0.223

   

Neutrophil

>3000/3000≥

0.21

0.067–0.658

0.007

0.298

0.071–1.240

0.097

Lymphocyte

>1800/1800≥

0.095

0.020–0.454

0.003

0.249

0.038–1.650

0.15

NLR

>2.645/2.645≥

0.4

0.159–1.010

0.052

   

CRP

>0.26/0.26≥

0.393

0.148–1.040

0.06

   

IL-6

>8.8/8.8≥

0.203

0.406–1.010

0.052

   

IgG

>1087/1087≥

0.107

0.038–0.302

<0.001

0.085

0.019–0.382

<0.001