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Table 1 Patient characteristics with and without ILD (n = 39)

From: Interstitial lung disease associated with adjuvant and neoadjuvant chemotherapy in early breast cancer

 

With ILD (n = 5)

Without ILD (n = 34)

p valueb)

Age (years)

   

 Median (range)

55 (38–63)

55 (29–74)

NS

eGFR (mL/min)

   

 Median (range)

90 (60–95)

79.5 (48–120)

NS

Smoking history

   

 Yes

0

4

 

 No

5

30

NS

Stage

   

 I

0

7

 

 IIA

2

13

 

 IIB

2

4

 

 IIIA

1

6

 

 IIIB

0

1

 

 IIIC

0

3

NS

Estrogen receptora)

   

 Positive

4

20

 

 Negative

1

14

NS

Progesterone receptora)

   

 Positive

3

12

 

 Negative

2

22

NS

HER 2 status

   

 Positive

0

15

 

 Negative

5

19

NS

Menopausal status

   

 Premenopausal

1

13

 

 Postmenopausal

4

21

NS

dd regimen administered

   

 Yes

5

13

 

 No

0

21

< .05

  1. ILD interstitial lung disease, eGFR estimated glomerular filtration rate, HER2 human epidermal growth factor receptor 2, dd dose-dense chemotherapy, NS not significant
  2. aDefined as an expression by immunochemistry in more than 10% of the cancer cells
  3. b< 0.05 were considered to indicate statistical significance