From: False-negative frozen section of sentinel nodes in early breast cancer (cT1-2N0) patients
 | Control (n = 60) | FNSN (n = 20) | P value | |
---|---|---|---|---|
Frozen section of lymph nodes | < 0.001 | |||
 Frozen section for relevant SNs and metastasis in nonrelevant SNs | 0 | 4 (20%) | ||
 False-negative results | 0 | 16 (80%) | ||
  Micrometastasis in SNs |  |  | 7 | |
   Metastasis in SNs and nonsentinel ALNs |  |  | 1 | |
   Metastasis only in SNs |  |  | 6 | |
  Macrometastasis in SNs |  |  | 9 | |
   Metastasis in SNs and nonsentinel ALNs |  |  | 1 | |
   Metastasis only in SNs |  |  | 8 | |
 True-negative results | 60 (100%) | 0 | ||
Lymphatic tumor emboli | 10 (17%) | 18 (90%) | < 0.001 | |
Number of relevant SNs for frozen section | 1 (0–9) | 2 (1–4) | 0.881 | |
Number of hot spots in lymphoscintigraphy | 1 (1–5) | 1 (1–4) | 0.570 | |
Total number of SNs during the 1st operation | 3 (1–13) | 5.5 (1–17) | 0.072 | |
Lymph node invasion | < 0.001 | |||
 Negative | 60 (100%) | 0 | ||
 Positive | 0 | 20 (100%) | ||
Resected lymph nodes (including SLNB and ALND) | 3 (1–13) | 23 (9–39) | < 0.001 | |
Positive lymph nodes (including SLNB and ALND) | 0 | 2 (1–7) | < 0.001 | |
Nodal stage | < 0.001 | |||
 N0 | 60 (100%) | 0 | ||
 N1 | 0 | 17 (85%) | ||
 N2 | 0 | 3 (15%) | ||
AJCC TNM stage | < 0.001 | |||
 Stage IA | 43 (72%) | 0 | ||
 Stage IIA | 17 (28%) | 12 (60%) | ||
 Stage IIB | 0 | 5 (25%) | ||
 Stage IIIA | 0 | 3 (15%) |