Fig. 7

CircLRP6 knockdown impedes PCa tumor growth and EMT in vivo. A subcutaneous tumor model was established. A Image of tumors (left panel) and in vivo growth curve (right panel). B Tumor weight of each group was analyzed at day 35. C qRT-PCR analysis of circLRP6, NRBP1, and miR-330-5p expression in tumors of mice from each group. D Western blot analysis of NRBP1, E-cadherin, and Vimentin protein levels in the tumor of mice from each group. E Representative images of IHC staining of NRBP and Ki-67 in tumors. *P < 0.05