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Fig. 1 | World Journal of Surgical Oncology

Fig. 1

From: MiR-194-5p enhances the sensitivity of nonsmall-cell lung cancer to doxorubicin through targeted inhibition of hypoxia-inducible factor-1

Fig. 1

Downregulation of miR-194-5p and upregulation of HIF-1 in hypoxia-induced NSCLC cells. a, b RT-qPCR was used to detect the expression levels of miR-194-5p and HIF-1 in hypoxia-induced NSCLC cell lines A549 and H460. c The expression of HIF-1 in hypoxia-induced NSCLC cell lines A549 and H460 was detected by western blot. d The CCK-8 method was performed to detect the viability of hypoxia-induced NSCLC cells and control NSCLC cells under different concentrations of DOX treatment. Data are presented as the mean ± SD. *P <0.05; **P <0.01; ***P <0.001

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