Fig. 8

CircASXL1 knockdown inhibited tumor growth by upregulating miR-1205 expression and downregulating GRIK3 expression in vivo. A, B CircASXL1 knockdown reduced the volume and weight of tumors. C, D CircASXL1 knockdown decreased circASXL1 expression, and increased miR-1205 expression in vivo. E CircASXL1 silencing downregulated GRIK3 protein expression. Significant differences were compared with two-tailed Student’s t tests. *P < 0.05