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Fig. 2 | World Journal of Surgical Oncology

Fig. 2

From: CircASXL1 knockdown represses the progression of colorectal cancer by downregulating GRIK3 expression by sponging miR-1205

Fig. 2

CircASXL1 silencing suppressed CRC progression. A CircASXL1 silencing reduced circASXL1 expression in SW480 and SW620 cells. B CircASXL1 knockdown repressed colony-forming ability of SW480 and SW620 cells. C, D CircASXL1 silencing induced cell arrest in G0/G1 phase and cell apoptosis in SW480 and SW620 cells. E, F CircASXL1 silencing downregulated Bcl-2 protein expression, and upregulated Bax protein expression. GI CircASXL1 absence inhibited the migration and invasion of SW480 and SW620 cells. Significant differences were compared with two-tailed Student’s t tests. *P < 0.05

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