Fig. 5
From: Long non-coding RNA XIST regulates ovarian cancer progression via modulating miR-335/BCL2L2 axis
XIST silence inhibited ovarian cancer cell proliferation, invasion, and migration. A The XIST knockdown was achieved by si-XIST, and the inhibition efficiency was affirmed by RT-qPCR. B BCL2L2 expression was inhibited by si-XIST. C, D MTT assays demonstrated that the knockdown of XIST strikingly lessened the proliferation of SKOV3 and OVCAR3 cell lines over time compared with the si-NC group. E, F The invasion and migration abilities of SKOV3 and OVCAR3 cell lines were inhibited by XIST knockdown. *P < 0.05, **P < 0.01