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Fig. 2 | World Journal of Surgical Oncology

Fig. 2

From: Comparative efficacy of intraoperative extracorporeal irradiated and alcohol-inactivated autograft reimplantation for the management of osteosarcomas—a multicentre retrospective study

Fig. 2

A Prechemotherapy X-ray examination showing osteolytic bone destruction in the right proximal tibia of an 18-year-old male patient who underwent joint preservation alcohol-inactivated autograft replantation for osteosarcoma. B Prechemotherapy coronal and sagittal MRI scans show a mix of high and low signals inside the medullary cavity of the tibia and surrounding soft tissue. C Two months after chemotherapy, the X-ray examination revealed that osteolytic bone destruction had markedly decreased. D The photo taken during surgery showed that the alcohol-inactivated autograft segment was filled with bone cement in the bone defect of the medial tibial plateau, replanted for reconstruction and firmly fixed by intramedullary nail fixation. E Radiographs taken 1 week after surgery showed solid internal fixation and joint preservation of the knee. F At 1 year after surgery, the X-ray examination revealed bone healing, but articular space narrowing was observed. G X-ray taken 3 years after limb salvage surgery. H At the 7-year follow-up, the X-ray examination of the right knee showed the condition of the alcohol-inactivated autograft segment. The subchondral bone was partially resorbed and fractured, narrowing of the space was observed, and arthrosis was indicated

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