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Table 4 Plasma levels of Hsp90α in patients with liver cancer with different clinicopathological characteristics

From: Plasma heat shock protein 90alpha as a biomarker for the diagnosis of liver cancer: in patients with different clinicopathologic characteristics

Characteristic Number Plasma Hsp90α level
(ng/mL)
P value
Sex Male 87 207.79 ± 144.91 0.153
Female 31 180.35 ± 140.34
Age < 60 66 221.23 ± 160.92 0.184
≥ 60 52 174.38 ± 114.34
History of hepatitis Yes 59 245.14 ± 181.37 0.024
No 59 156.02 ± 68.42
History of cirrhosis Yes 39 269.71 ± 206.83 0.040
No 79 166.45 ± 80.85
Active stage of liver disease Yes* 17 221.05 ± 148.62 0.040
No 17 134.07 ± 26.79
Child-Pugh A/B 59 155.21 ± 100.03 0.025
C 59 255.26 ± 171.48
Morbidity 1st Occurrence 118 217.75 ± 104.27 0.042
Recurrence 33 136.12 ± 49.23
Source Primary 91 190.38 ± 125.72 0.038
Secondary 27 249.78 ± 154.61
Primary organs of secondary liver cancer Colorectal 10 221.90 ± 192.85 0.896
Stomach 3 133.89 ± 41.05
Pancreas 4 205.56 ± 137.48
Other 10 220.12 ± 186.96
Size of focal liver lesions < 3 cm 10 123.31 ± 26.01 0.006
3 cm 22 177.71 ± 54.33
Extrahepatic metastasis Yes 33 277.20 ± 183.01 < 0.001
No 22 115.11 ± 61.26
N/A 63 212.24 ± 133.91
  1. * HBV DNA > 104. Bold P values are significant.